Peer-Reviewed Publications

  1. Aryal, G.*; Battle, C. H.*; Grusenmeyer, T.; Zhu, M.; Jayawickramarajah, J. A Napthalimide Derived Fluorescence Sensor for Solid-Phase Screening of Cucurbit[7]uril-Guest Interactions. Chem. Comm. 2016 52, 2307-2310.

    *These authors contributed equally to this work

    DOI: 10.1039/C5CC08350H | Abstract

  2. Chu, X.; Battle, C.; Zhang, N.; Aryal, G. H.; Madhusoodanan, M.; Jayawickramarajah, J. A Bile acid conjugated DNA chimera that conditionally inhibits carbonic anhydrase-II in the presence of microRNA-21. Bioconjugate Chem. 2015, 26 (8), 1606-1612.

    DOI: 10.1021/acs.bioconjchem.5b00231 | Abstract

  3. Su, X.; Kuang, L.; Battle, C.; Shaner, T.; Mitchell, B. S.; Fink, M. J.; Jayawickramarajah, J., Mild Two-Step Method to Construct DNA-Conjugated Silicon Nanoparticles: Scaffolds for the Detection of MicroRNA-21. Bioconjugate Chem. 2014, 25 (10), 1739–1743.

    DOI: 10.1021/bc5004026 | Abstract

  4. Battle, C. H.; Chu, X.; Jayawickramarajah, J., Oligonucleotide-Based Systems for Input-Controlled and Non-Covalently Regulated Protein-Binding. Supramolecular Chemistry. 2013, 25 (12), 848-862.

    DOI: 10.1080/10610278.2013.810337 | Abstract

  5. Battle, C. H.; Jayawickramarajah, J., Supramolecular Approaches for Inhibition of Protein-Protein and Protein/DNA Interactions. In Supramolecular Chemistry: From Molecules to Nanomaterials, Steed, J. W.; Gale, P. A., Eds. John Wiley and Sons: 2012; Vol. 4, pp 1885-1908.

    DOI: 10.1002/9780470661345 | Abstract

  6. Mishur, R. J.; Griffin, M. E.; Battle, C. H.; Shan, B.; Jayawickramarajah, J., Molecular recognition and enhancement of aqueous solubility and bioactivity of CD437 by [beta]-cyclodextrin. Bioorg. Med. Chem. Lett. 2011, 21 (2), 857-860.

    DOI: 10.1016/j.bmcl.2010.11.073 | Abstract

A naphthalimide derived fluorescent sensor for solid-phase screening of cucurbit[7]uril–guest interactions

DOI: 10.1039/C5CC08350H

A naphthalimide based fluorescent sensor displaying a significant increase in emission upon binding CB[7] with notable pH stability was developed and utilized in a surface-bound displacement assay for the rapid detection of CB[7] encapsulation of therapeutically relevant drug classes. Previously unknown binders with moderate to strong affinities were discovered.

Updated June 2016, ® Cooper Battle